Controlled study 2012; Improvement of sperm quality after micronutrient supplementation; Imhof M. et al.; published in e-SPEN , Volume 7, Issue 1, February 2012; patients (n = 205): PROFERTIL®group: n = 132, control group: n = 73; inclusion criteria: ≥ 1 year of subfertility and ≥ 2 pathological semen analyses; exclusion criteria: aspermia, varicocele, azoospermia, urogenital infections. Pregnancy rate control group = 15.07%